A regular, semi-automatic assault rifle with all of the highest level mods equipped deals around 99 damage. The assault rifle is a weapon in Fallout 4. 25 Best Fallout 4 Weapon Mods To Dominate The Wasteland 15 Best Rifles in Fallout 4 (And Where To Get Them) It can be buffed up a decent bit with one of the scav magazines.

Throatslicer from the nuka-world dlc is probably the best melee option in the game. The Best Weapons In Fallout 4 (And Where To Find Them) The best weapons in Fallout 4 and where to find them It's essentially a Fat Man that has been modified. Arguably the most powerful weapon in the game is the Nuka-Nuke Launcher found in Nuka-World.

Arguably the best weapon in Fallout 4, can be found just to the southeast of Oberland Station, or slightly northwest of Diamond City.